Stereospecific determination and in vivo monodeiodination of thyroxine enantiomers in euthyroid man
β Scribed by Ian D. Hay; Colum A. Gorman; Kenneth D. Burman; Nai-Siang Jiang
- Book ID
- 118948961
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 732 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1532-8600
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π SIMILAR VOLUMES
The purposes of this work were (1) to develop a high performance liquid chromatographic (HPLC) assay for the enantiomers of thalidomide in blood, (2) to study their inversion and degradation in human blood, and (3) to study the phannacokinetics of (+)-(R)and (-)-(S)-thalidomide after oral administra
L-thyroxine and D-thyroxine were separated on ligand exchange chiral thin layer chromatographic plates, using a solvent system consisting of acetonitrile: methanol: water 60: 15: 15 v/v, at a wavelength of 254 nm. The methodology, chiral recognition mechanism@) involved and its application are discu