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Optical purity determination of thyroxine enantiomers in bulk materials by chiral thin layer chromatography

✍ Scribed by Hassan Y. Aboul-Enein; Vince Serignese


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
177 KB
Volume
8
Category
Article
ISSN
0269-3879

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✦ Synopsis


L-thyroxine and D-thyroxine were separated on ligand exchange chiral thin layer chromatographic plates, using a solvent system consisting of acetonitrile: methanol: water 60: 15: 15 v/v, at a wavelength of 254 nm. The methodology, chiral recognition mechanism@) involved and its application are discussed,