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Enantiomeric separation and optical purity determination of thyroxine enantiomers in bulk and pharmaceutical formulations

✍ Scribed by Laila I Abou-Basha; Hassan Y Aboul-Enein


Book ID
113199208
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
343 KB
Volume
70
Category
Article
ISSN
0031-6865

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Optical purity determination of thyroxin
✍ Hassan Y. Aboul-Enein; Vince Serignese πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 177 KB πŸ‘ 1 views

L-thyroxine and D-thyroxine were separated on ligand exchange chiral thin layer chromatographic plates, using a solvent system consisting of acetonitrile: methanol: water 60: 15: 15 v/v, at a wavelength of 254 nm. The methodology, chiral recognition mechanism@) involved and its application are discu