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Stereospecific conversion of peptides into .beta.-lactams

โœ Scribed by Baldwin, Jack E.; Au, Andrew; Christie, Michael; Haber, Stephen B.; Hesson, David


Book ID
126883271
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
234 KB
Volume
97
Category
Article
ISSN
0002-7863

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A stereospecific conversion of berberine
โœ Maurice Shamma; David M. Hindenlang; Tai-Teh Wu; Jerome L. Moniot ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 195 KB

The conversion of berberine (1) into a I:2 mixture of (A)-c(-hydrastine (3) and (+)-6hydrastine (4) through the intermediacy of 8-methoxyberberinephenolbetaine (2) has been recorded.2 The betaine 2 can be obtained by means of the ferricyanide oxidation of berberine, followed by treatment with meth