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Total synthesis of .beta.-lactam antibiotics. VIII. Stereospecific total synthesis of (+-)-1-carbacephalothin

โœ Scribed by Guthikonda, R. N.; Cama, L. D.; Christensen, B. G.


Book ID
127015309
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
253 KB
Volume
96
Category
Article
ISSN
0002-7863

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Total synthesis of ฮฒ-lactam antibiotics
โœ Ronald W. Ratcliffe; B.G. Christensen ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 215 KB

a-Thioformamido-diethylphosphonoacetates (I) have been found to condense with lcbloro-2-propanones in the presence of base to give 6H-1,3-thiazine-4-carboxylates (II).