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Cell-free biosynthesis of penicillins. Conversion of peptides into new .beta.-lactam antibiotics

โœ Scribed by Bahadur, Gulam A.; Baldwin, Jack E.; Usher, John J.; Abraham, Edward P.; Jayatilake, Gamini S.; White, Robert L.


Book ID
126100739
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
258 KB
Volume
103
Category
Article
ISSN
0002-7863

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Studies on ฮฒ-lactam antibiotics. I. A no
โœ Takashi Kamiya; Tsutomu Teraji; Yoshihisa Saito; Masashi Hashimoto; Osamu Nakagu ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 217 KB

The sulfenic acid intermediate (A) formed by a thermal sigmatropic rearrangement of penicillin sulfoxides (I) has been trapped either intramolecularly or intermolecularly by several methods. 1) Our efforts have been directed to the preparation of a key intermediate useful for syntheses of modified B