## Abstract A convergent and efficient total synthesis of stagonolide C (**1**), a phytotoxic metabolite, was achieved (__Schemesโ 2__ and __3__) The synthesis exploited the high configuration control in the __Prins__ cyclization along with alkene rearrangement and ringโclosing metathesis as key ste
Stereoselective total synthesis of stagonolide E
โ Scribed by Gowravaram Sabitha; P. Padmaja; P. Narayana Reddy; Surender Singh Jadav; J.S. Yadav
- Book ID
- 104098353
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 234 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Jacobsen's kinetic resolution, Sharpless epoxidation, Stille-Gennari, and Yamaguchi lactonization as key reactions.
๐ SIMILAR VOLUMES
First stereoselective total synthesis of nonenolide stagonolide G involving a convergent strategy is described. The key reactions include Keck allylation and Grubbs ring closing metathesis reaction.
## Abstract A simple asymmetric total synthesis of stagonolide G (**1**) is described. Asymmetric dihydroxylation, regioselective epoxide ring opening, and vinyl __Grignard__ reactions are involved in generating the stereogenic centers C(4) and C(8), followed by __GrubbsโIIโ__catalyzed ringโclosing