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Stereoselective synthesis of the C-4 linked imidazole nucleosides using modified Mitsunobu reaction

✍ Scribed by Shinya Harusawa; Yoshihiko Murai; Hideki Moriyama; Hirofumi Ohishi; Ryuji Yoneda; Takushi Kurihara


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
201 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract The __Mitsunobu__ reaction is an important tool in carbocyclic nucleoside chemistry for the direct coupling of alcohols with heterocyclic bases under mild conditions. Chemical evidences for an unusual competitive __O__^2^‐ __vs. N__^1^‐alkylation of 3‐substituted pyrimidines is presente