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Stereoselective synthesis of pyrazoline derivatives by 1,3-dipolar cycloaddition of diazoalkanes to α,β-unsaturated carbonyl derivatives of sugars

✍ Scribed by Manuel Mancera; Enrique Rodriguez; Isaac Roffé; Juan A. Galbis


Book ID
107726047
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
570 KB
Volume
210
Category
Article
ISSN
0008-6215

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Synthesis of spiro-1-pyrazolines by the
✍ Artur M. S. Silva; José A. S. Cavaleiro; Albert Lévai; Tamás Patonay 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 641 KB

## Abstract 1,3‐Dipolar cycloadditions of exocyclic α,β‐unsaturated ketones 1‐22 with diazomethane afforded spiro‐1‐pyrazolines 23‐44 in a diastereospecific reaction. The structure and stereochemistry of each compound synthesised has been elucidated by nmr spectroscopic measurements and other analy