Synthesis of spiro-1-pyrazolines by the
✍
Artur M. S. Silva; José A. S. Cavaleiro; Albert Lévai; Tamás Patonay
📂
Article
📅
1999
🏛
Journal of Heterocyclic Chemistry
🌐
English
⚖ 641 KB
## Abstract 1,3‐Dipolar cycloadditions of exocyclic α,β‐unsaturated ketones 1‐22 with diazomethane afforded spiro‐1‐pyrazolines 23‐44 in a diastereospecific reaction. The structure and stereochemistry of each compound synthesised has been elucidated by nmr spectroscopic measurements and other analy