Stereoselective synthesis of non-proteinogenic amino acids
β Scribed by Andrew N Bowler; Paul M Doyle; Peter B Hitchcock; Douglas W Young
- Book ID
- 108378683
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 589 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
A general, stereospecific, synthesis of S,Y-unsaturated a-amino acids using the S-anion derived from aspartic acid is described . S,Y-Unsaturated amino acids have been found to be reversible or irreversible inhibitors of a number of enzymes,' and this has prompted a number of racemic syntheses of th
By treating N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroamino acid derivatives with different reactants under different conditions, a variety of new amino acids are obtained, viz. (i) a-alcoxy-a-amino acids, (ii) a,a-diamino acids and (iii) novel b-substituted dehydroamino acids.