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Stereoselective synthesis of (±)-methyl nonactate and (±)-methyl 8-epi-nonactate.

✍ Scribed by Barry Lygo; Norval O'Connor

Book ID
104227262
Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
244 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis

+Metbyl nonactate (2) and (i)-methyl S-epi-nonactate (3), synthetic precursors to the antibiitic nonactin have been syntbcsised, employing the reaction of substituted epoxides with dianions derived from p-ketoesm as the key carbon-carbon bond-forming step.

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