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Stereoselective synthesis of (-)-hydroxyclemastine as a versatile intermediate for the h1receptor antagonist clemastine

✍ Scribed by Jung Wha Jung; Hee-Doo Kim


Book ID
105672828
Publisher
Springer
Year
2007
Tongue
English
Weight
466 KB
Volume
30
Category
Article
ISSN
0253-6269

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## Abstract The indene derivative 7 and the 1,2,2,3‐tetrasubstituted cyclopentane derivative 8 have been synthesized in three steps starting from the Hajos‐Wiechert ketone 1. magnified image