## Abstract 1‐[^13^CD~3~]‐9‐__cis__‐Retinoic acid was prepared in 8 steps from 2,6‐dimethylcyclohexanone. Alkylation of 2,6‐dimethylcyclohexanone under LiHMDS/MnBr~2~/^13^CD~3~I gave the corresponding labeled 2‐[^13^CD~3~]‐2,2,6‐trimethylcyclohexanone 4 in good yield. Further functionalization of 4
Stereoselective synthesis of 9-cis-retinoic acid by suzuki reaction
✍ Scribed by Yolanda Pazos; Angel R. de Lera
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 292 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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## Abstract All‐__trans__‐Retinoic acid [11,12‐^3^H(N)] was photochemically isomerized using a fluorescent source to afford a mixture of isomeric retinoic acids, from which 9‐__cis__‐retinoic acid[11,12‐^3^H(N)] was isolated by reversed‐phase HPLC. The identity of 9‐__cis__‐retinoic acid [11, 12‐^3