Stereoselective reduction of α-hydroxy oxime ethers: a convenient route to cis1,2-amino alcohols
✍ Scribed by Arun K. Ghosh; Sean P. McKee; William M. Sanders
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 258 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Summarv
Reduction of cychc a-hydroxyketoxlmes with borane provides an excellent, high yleldmg, reglo-and stereoselectlve route to a-1,2-amlnoalcohols.
📜 SIMILAR VOLUMES
The electroreduction of ketones together with O-methyl oximes gave intermolecularly coupled products, 2-methoxyamino alcohols, which were easily reduced to 2-amino alcohols. Reductive cross coupling of C=O group with C=N group will provide a convenient route to the synthesis of 2amino alcohols (eql
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