✦ LIBER ✦

Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes

✍ Scribed by David W. Potter; Wayne Levin; Dene E. Ryan; Paul E. Thomas; Donald J. Reed

Book ID: 115777576
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 571 KB
Volume: 33
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(84)90316-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular structure of 1-(2-chloroethyl)

Molecular structure of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

✍ Smith, H. Warren; Camerman, Arthur; Camerman, Norman 📂 Article 📅 1978 🏛 American Chemical Society 🌐 English ⚖ 489 KB

Physiologic disposition of 1-(2-chloroet

Physiologic disposition of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (MeCCNU) in man

✍ Robert W. Sponzo; Vincent T. Devita; Vincent T. Oliverio 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 466 KB 👁 2 views

The physiologic disposition of radioactive-labelled CCNU and MeCCNU was studied in patients receiving these drugs as part of their early clinical trial. CCNU was given orally in doses of 30-100 mg/m2 a n d MeCCNU in doses of 120-290 mg/m?. With both drugs, significant plasma levels of radioactivity

Microsomal monooxygenation of the carcin

Microsomal monooxygenation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Synthesis and identification of cis and trans monohydroxylated products

✍ May, Hubert E.; Boose, Richard; Reed, Donald J. 📂 Article 📅 1975 🏛 American Chemical Society 🌐 English ⚖ 844 KB

Hydroxylation of the carcinostatic 1-(2-

Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes

✍ Hubert E. May; Richard Boose; Donald J. Reed 📂 Article 📅 1974 🏛 Elsevier Science 🌐 English ⚖ 393 KB

Inhibition of human glutathione reductas

Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea : A crystallographic analysis

✍ P. Andrew KARPLUS; R. Luise KRAUTH-SIEGEL; R. Heiner SCHIRMER; Georg E. SCHULZ 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

Initial clinical trials with methyl-ccnu

Initial clinical trials with methyl-ccnu 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (meccnu)

✍ Robert C. Young; Michael D. Walker; George P. Canellos; Philip S. Schein; Bruce 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 2 views