Stereoselective Michael Addition of Trimethyl Aluminum to Nitro Acrylates: A Route to 2-Methyl-3-amino Propionic Acid.
β Scribed by Uwe Eilitz; Frank Lessmann; Oliver Seidelmann; Volkmar Wendisch
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 109 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Introduction. ~ Stereoselective C-C bond forming reactions catalyzed by chiral transition-metal complexes are a topic of fundamental importance [l]. In 1986, Hayashi and Zto reported an elegant asymmetric synthesis of dihydrooxazoles by an efficient gold(1)-catalyzed coupling of aldehydes with 2-iso