𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereoselective disposition and tissue distribution of carvedilol enantiomers in rats

✍ Scribed by Masayoshi Fujimaki

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
673 KB
Volume
4
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Stereoselective disposition of tiaprofen
Stereoselective disposition of tiaprofenic acid enantiomers in rats
✍ K. Erb; R. Brugger; K. Williams; G. Geisslinger πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 100 KB πŸ‘ 2 views

The pharmacokinetics and metabolic chiral inversion of the S(+)-and R(-)-enantiomers of tiaprofenic acid (S -TIA, R-TIA) were assessed in vivo in rats, and in addition the biochemistry of inversion was investigated in vitro in rat liver homogenates. Drug enantiomer concentrations in plasma were inve

Stereoselective plasma protein binding a
Stereoselective plasma protein binding and target tissue distribution of clausenamide enantiomers in rats
✍ Chuan Jiang Zhu; Jun Tian Zhang πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 188 KB πŸ‘ 2 views

Stereoselective differences in pharmacokinetics between clausenamide (CLA) enantiomers have been found after intravenous and oral administration of each enantiomer to rats. The differences could be associated with protein binding of CLA enantiomers. By equilibrium dialysis methods, the binding of CL

Disposition of enantiomers of sulpiride
Disposition of enantiomers of sulpiride in humans and rats
✍ Ayako Kamizono; Nobuo Inotsume; Shoji Fukushima; Masahiro Nakano; Yoshio Okamoto πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 322 KB πŸ‘ 2 views

## Abstract Pharmacokinetics of sulpiride enantiomers after intravenous administration of (Β±)‐, (+)‐, and (βˆ’)‐sulpiride was examined in humans and rats. Pharmacokinetic profiles were similar in (+)‐ and (βˆ’)‐enantiomers after intravenous administration of (Β±)‐sulpiride. Metabolic inversion at a chir

Stereoselective disposition of ibuprofen
Stereoselective disposition of ibuprofen and flurbiprofen in rats
✍ Romualda D. Knihinicki; Richard O. Day; Garry G. Graham; Kenneth M. Williams πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 655 KB

R)-2-Arylpropionates are often inverted to the pharmacologically active S-enantiomers in vivo, although there is significant interspecies variability in inversion. In order to provide a basis for determining the biochemical consequences of this unique process using rats as a model, it was important