✦ LIBER ✦

Stereoselective disposition of hydroxychloroquine and its metabolites in rats

✍ Scribed by Yimin Wei; Gloria A. Nygard; Shari L. Ellertson; Shoukry K.W. Khalil

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 576 KB
Volume: 7
Category: Article
ISSN: 0899-0042
DOI: 10.1002/chir.530070807

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereoselective disposition of ibuprofen

Stereoselective disposition of ibuprofen and flurbiprofen in rats

✍ Romualda D. Knihinicki; Richard O. Day; Garry G. Graham; Kenneth M. Williams 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 655 KB

R)-2-Arylpropionates are often inverted to the pharmacologically active S-enantiomers in vivo, although there is significant interspecies variability in inversion. In order to provide a basis for determining the biochemical consequences of this unique process using rats as a model, it was important

Stereoselective single-dose kinetics of

Stereoselective single-dose kinetics of citalopram and its metabolites in rats

✍ Fredrik C. Kugelberg; Björn Carlsson; Johan Ahlner; Finn Bengtsson 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB

Stereoselective determination of hydroxy

Stereoselective determination of hydroxychloroquine and its metabolites in human urine by liquid-phase microextraction and CE

✍ Anderson Rodrigo Moraes de Oliveira; Carmen Dickow Cardoso; Pierina Sueli Bonato 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB

## Abstract Liquid‐phase microextraction based on polypropylene hollow fibers and CE were applied for the chiral determination of hydroxychloroquine (HCQ) and its metabolites (desethylchloroquine, DCQ; desethylhydroxychloroquine, DHCQ; bisdesethylchloroquine, BDCQ) in human urine. The analytes were

Stereoselective disposition of tiaprofen

Stereoselective disposition of tiaprofenic acid enantiomers in rats

✍ K. Erb; R. Brugger; K. Williams; G. Geisslinger 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB 👁 2 views

The pharmacokinetics and metabolic chiral inversion of the S(+)-and R(-)-enantiomers of tiaprofenic acid (S -TIA, R-TIA) were assessed in vivo in rats, and in addition the biochemistry of inversion was investigated in vitro in rat liver homogenates. Drug enantiomer concentrations in plasma were inve

Stereoselective disposition and tissue d

Stereoselective disposition and tissue distribution of carvedilol enantiomers in rats

✍ Masayoshi Fujimaki 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 673 KB

Enantioselective determination of hydrox

Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(−)-hydroxychloroquine ratio

✍ Hiltrud Fieger; Joanna Iredale; Dr. Irving W. Wainer 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB 👁 1 views