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Stereocontrolled Synthesis of the Quinaldic Acid Macrocyclic System of Thiostrepton

✍ Scribed by K. C. Nicolaou; Brian S. Safina; Christian Funke; Mark Zak; Frédéric J. Zécri

Book ID
101372844
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
123 KB
Volume
41
Category
Article
ISSN
0044-8249

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📜 SIMILAR VOLUMES

Total Synthesis of Thiostrepton, Part 2:
Total Synthesis of Thiostrepton, Part 2: Construction of the Quinaldic Acid Macrocycle and Final Stages of the Synthesis
✍ K. C. Nicolaou; Mark Zak; Brian S. Safina; Sang Hyup Lee; Anthony A. Estrada 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 428 KB 👁 1 views

In the preceding Communication in this issue [1] we described the construction of the thiazoline-containing macrocycle 2 as an advanced intermediate toward the total synthesis of thiostrepton (1). Herein we report the construction of suitable dipeptide (8, Scheme 1) and quinaldic acid (22, Scheme 2)