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Total Synthesis of Thiostrepton. Part 1. Construction of the Dehydropiperidine/Thiazoline-Containing Macrocycle.

✍ Scribed by K. C. Nicolaou; Brian S. Safina; Mark Zak; Anthony A. Estrada; Sang Hyup Lee

Book ID: 101962313
Publisher: John Wiley and Sons
Year: 2004
Weight: 7 KB
Volume: 35
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200449205

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Total Synthesis of Thiostrepton, Part 1:

Total Synthesis of Thiostrepton, Part 1: Construction of the Dehydropiperidine/Thiazoline-Containing Macrocycle

✍ K. C. Nicolaou; Brian S. Safina; Mark Zak; Anthony A. Estrada; Sang Hyup Lee 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB 👁 1 views

Total Synthesis of Thiostrepton, Part 1:

Total Synthesis of Thiostrepton, Part 1: Construction of the Dehydropiperidine/Thiazoline-Containing Macrocycle

✍ K. C. Nicolaou; Brian S. Safina; Mark Zak; Anthony A. Estrada; Sang Hyup Lee 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 431 KB

Synthetic Studies on Thiostrepton: Const

Synthetic Studies on Thiostrepton: Construction of Thiostrepton Analogues with the Thiazoline-Containing Macrocycle

✍ K. C. Nicolaou; Marta Nevalainen; Mark Zak; Stephan Bulat; Marco Bella; Brian S. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 279 KB

Synthetic Studies on Thiostrepton: Const

Synthetic Studies on Thiostrepton: Construction of Thiostrepton Analogues with the Thiazoline-Containing Macrocycle

✍ K. C. Nicolaou; Marta Nevalainen; Mark Zak; Stephan Bulat; Marco Bella; Brian S. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 280 KB

Total Synthesis of Thiostrepton. Part 2.

Total Synthesis of Thiostrepton. Part 2. Construction of the Quinaldic Acid Macrocycle and Final Stages of the Synthesis.

✍ K. C. Nicolaou; Mark Zak; Brian S. Safina; Sang Hyup Lee; Anthony A. Estrada 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 7 KB

Total Synthesis of Thiostrepton, Part 2:

Total Synthesis of Thiostrepton, Part 2: Construction of the Quinaldic Acid Macrocycle and Final Stages of the Synthesis

✍ K. C. Nicolaou; Mark Zak; Brian S. Safina; Sang Hyup Lee; Anthony A. Estrada 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 428 KB 👁 1 views

In the preceding Communication in this issue [1] we described the construction of the thiazoline-containing macrocycle 2 as an advanced intermediate toward the total synthesis of thiostrepton (1). Herein we report the construction of suitable dipeptide (8, Scheme 1) and quinaldic acid (22, Scheme 2)