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Stereocontrolled synthesis of the C79–C96 fragment of symbiodinolide

✍ Scribed by Hiroyoshi Takamura; Junki Ando; Takashi Abe; Takeshi Murata; Isao Kadota; Daisuke Uemura


Book ID
108285032
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
305 KB
Volume
49
Category
Article
ISSN
0040-4039

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Stereoselective synthesis of the C14–C24
✍ Hiroyoshi Takamura; Yuichiro Kadonaga; Isao Kadota; Daisuke Uemura 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 311 KB

Symbiodinolide is a polyol macrolide isolated from the marine dinoflagellate Symbiodinium sp. in 2007. The C14-C24 fragment of symbiodinolide possessing the 17R/18R/21R absolute configuration, which was obtained as one of the degraded products of symbiodinolide, was synthesized stereoselectively fro

Determination of absolute configuration
✍ Chunguang Han; Yoshi Yamano; Masaki Kita; Hiroyoshi Takamura; Daisuke Uemura 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 431 KB

The degradation product C14ÀC23 2 was obtained using ethenolysis with the 2nd-generation Hoveyda-Grubbs catalyst from 62-membered lactone in symbiodinolide (1). The absolute configurations of three chiral centers in fragment 2 were assigned as 17R, 18R, and 21R by a combination of J-based configurat