Stereocontrolled synthesis of isocomene by a novel photocycloaddition?fragmentation strategy
β Scribed by Rawal, Viresh H.; Dufour, Claire; Eschbach, Andrew
- Book ID
- 127116552
- Publisher
- The Royal Society of Chemistry
- Year
- 1994
- Tongue
- English
- Weight
- 271 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-4936
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Financial support for this work was provided by the NCI (R01 CA126827), the American Cancer Society (Research Scholar Grant), the Elsa Pardee Foundation, Amgen, and GlaxoSmithKline. Marianne Lalonde provided assistance with X-ray crystallographic analysis. W.J.M. thanks Abbott Laboratories for a gra
4.n]Metacyclophanes 6 (n = 2 -6), [4.n]paracyclophanes 7 (n = 3 -6), [4~1](4,4')biphenylophanes 8 (n = 3, 4), and C2.3.2.41paracyclophane 9 were obtained from appropriate 1,2-ethano-[2.n]cyclophanes 1 -5 by Birch reduction. Some strained cyclophanes, like la, lb, and 2a, gave linear open-chain compo