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Synthesis of Novel 3′- C -Hydroxymethyl Nucleosides by a Convergent Strategy

✍ Scribed by J⊘rgensen, Pia N⊘rregaard; Wengel, Jesper


Book ID
126564451
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
181 KB
Volume
16
Category
Article
ISSN
0732-8311

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AbstractÐThe two diastereomers of a 3-oxabicyclo[3.1.0]hexan-2-ol 21a±b with the cyclopropane ring substituted by a hydroxymethyl group were synthesized from both products 17a and 18a obtained from the bromohydroxylation of epoxide 16a derived from 3-oxabicyclo[3.2.0]hept-6-en-2-one 15. This prepara