Synthesis of (−)-Okilactomycin by a Prins-Type Fragment-Assembly Strategy

✍ Scribed by Dr. Jason M. Tenenbaum; William J. Morris; Daniel W. Custar; Prof. Dr. Karl A. Scheidt

• Book ID: 101572944
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 332 KB
• Volume: 50
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.201102037

✦ Synopsis

Financial support for this work was provided by the NCI (R01 CA126827), the American Cancer Society (Research Scholar Grant), the Elsa Pardee Foundation, Amgen, and GlaxoSmithKline. Marianne Lalonde provided assistance with X-ray crystallographic analysis. W.J.M. thanks Abbott Laboratories for a graduate fellowship. We thank FMCLithium and Wacker Chemical for providing reagents, Dr. Chris Holmquist for assistance with chromatography, and Astellas Pharma for providing the spectroscopic data of natural (+)-okilactomycin.