𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereocontrolled Synthesis and Pharmacological Evaluation of cis-2,6-Diphenethyl-1-azabicyclo[2.2.2]octanes as Lobelane Analogues

✍ Scribed by Zheng, Guangrong; Dwoskin, Linda P.; Deaciuc, Agripina G.; Crooks, Peter A.

Book ID
111891442
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
826 KB
Volume
74
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis and muscarinic M3 pharmacologi
Synthesis and muscarinic M3 pharmacological activities of 1-azabicyclo[2.2.2]octan-3-one oxime derivatives
✍ Ralf Plate; Marc J.M. Plaum; Thijs de Boer; John S. Andrews πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 634 KB

A series of 1-azabicyclo[2.2.2]octan-3-one oximes and related 1-azabicyclo-[2.2.2]-octan-3-one hydroxylamines were synthesized and tested for muscarinic M3 activity. All compounds showed at least some muscarinic binding properties, however, only one member of the series demonstrated mucarinic M3 ago

An Improved Synthesis of 1,3,3-Trimethyl
An Improved Synthesis of 1,3,3-Trimethyl-2-azabicyclo[2.2.2]octane and Its Nitroxyl Radical Product, a Rigid Analogue of TEMPO
✍ Bakunov, Stanislav ;Tkachev, Alexey πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 246 KB

## Abstract A new synthetic approach for the production of isoquinuclidine 6 from dipentene (__rac__‐limonene, 1) is described. The nitroxyl 5, a rigid analogue of TEMPO, has been prepared from 6 in 87% yield.