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Stereocontrolled catalytic asymmetric reduction of ketones with oxazaborolidines derived from new chiral amino alcohols

✍ Scribed by Kim, Yong Hae; Park, Doo Han; Byun, Il Suk; Yoon, I. K.; Park, C. S.


Book ID
125442825
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
233 KB
Volume
58
Category
Article
ISSN
0022-3263

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Catalytic asymmetric borane reduction of
✍ Zhou Yong-Gui; Hou Xue-Long; Dai Li-Xin πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 264 KB πŸ‘ 1 views

Easily available D-(+)-camphor-derived chiral mercapt\*alcohols 2 and 3 were employed for catalytic asymmetric borane reduction of aromatic ketones. Moderate enantioselectivities with e.e. 20.2-72.1% were obtained with 10 mol% catalyst. Opposite asymmetric induction was achieved' when mercaptc-alcoh