Catalytic asymmetric borane reduction of
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Zhou Yong-Gui; Hou Xue-Long; Dai Li-Xin
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Article
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2010
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John Wiley and Sons
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English
β 264 KB
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Easily available D-(+)-camphor-derived chiral mercapt\*alcohols 2 and 3 were employed for catalytic asymmetric borane reduction of aromatic ketones. Moderate enantioselectivities with e.e. 20.2-72.1% were obtained with 10 mol% catalyst. Opposite asymmetric induction was achieved' when mercaptc-alcoh