Catalytic Enantioselective Reduction of Prochiral Ketones with Chiral Ferrocenyl Amino Alcohols
β Scribed by Wei-Yi Chen; Jun Lu; Zong-Xuan Shen; Ya-Wen Zhang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 347 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0256-7660
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π SIMILAR VOLUMES
Easily available D-(+)-camphor-derived chiral mercapt\*alcohols 2 and 3 were employed for catalytic asymmetric borane reduction of aromatic ketones. Moderate enantioselectivities with e.e. 20.2-72.1% were obtained with 10 mol% catalyst. Opposite asymmetric induction was achieved' when mercaptc-alcoh
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