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Stereochemistry and Fate of Hydrogen Atoms in the Diol-Dehydratase-Catalyzed Dehydration of meso-Butane-2,3-diol
β Scribed by Paolo Manitto; Giovanna Speranza; Gabriele Fontana; Antonietta Galli
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- German
- Weight
- 168 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0018-019X
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18 O-Substituted propane-1,2-diols and meso-butane-1,2-diols were synthesized and fed to growing cells of Lactobacillus brevis. Propan-1-ol and butan-2-ol, prepared from such diols through diol-dehydratase-catalyzed dehydration followed by intracellular reduction, were analyzed for their 18 O-conten
with respect to the catalyst concentration is first. The reaction mechanism supposes the formation of a complex between the substrate and the catalyst active form . Subsequently, the complex thus formed slowly decomposes in the rate determining step to give carbonium ions and ruthenium hydride, sinc