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Stereochemical Sensitivity of the Human UDP-glucuronosyltransferases 2B7 and 2B17

✍ Scribed by Bichlmaier, Ingo; Siiskonen, Antti; Finel, Moshe; Yli-Kauhaluoma, Jari


Book ID
121196981
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
169 KB
Volume
49
Category
Article
ISSN
0022-2623

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Glucuronidation catalyzed by UDP-glucuronosyltransferase (UGT) enzymes is an important pathway in the metabolism of drugs as well as environmental chemicals. In this study, protein-protein interactions between human UGT2B7 and UGT1As and their effects on the enzymatic activities were investigated us