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Nicotine Glucuronidation and the Human UDP-Glucuronosyltransferase UGT2B10

✍ Scribed by Kaivosaari, S.; Toivonen, P.; Hesse, L. M.; Koskinen, M.; Court, M. H.; Finel, M.

Book ID
111919756
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2007
Tongue
English
Weight
529 KB
Volume
72
Category
Article
ISSN
0026-895X

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Glucuronidation catalyzed by UDP-glucuronosyltransferase (UGT) enzymes is an important pathway in the metabolism of drugs as well as environmental chemicals. In this study, protein-protein interactions between human UGT2B7 and UGT1As and their effects on the enzymatic activities were investigated us