Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17
✍ Scribed by Bichlmaier, Ingo; Siiskonen, Antti; Kurkela, Mika; Finel, Moshe; Yli-Kauhaluoma, Jari
- Book ID
- 120476293
- Publisher
- Walter de Gruyter GmbH & Co. KG
- Year
- 2006
- Tongue
- English
- Weight
- 168 KB
- Volume
- 387
- Category
- Article
- ISSN
- 1431-6730
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## Abstract Stereoselective metabolism of propranolol side‐chain glucuronidation was studied for two recombinant human uridine diphosphate glucuronosyltransferases (UGTs), UGT1A9 and UGT2B7. The __S__‐ and __R__‐propranolol side‐chain glucuronides produced in the incubation mixtures were assayed si