Stepwise Replication of a Tröger's Base Analogue
✍ Scribed by Braja G. Bag; Günter von Kiedrowski
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 77 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Under acidic conditions the enantiomers of Tröger's base 1 (2,8-dimethyl-6 H,12 H-5,11-methanodibenzo[b,f][1,5]diazozine) are subject to enantiomerization. During enantioselective dynamic electrokinetic chromatography using 10 mM hydroxypropyl-beta-cyclodextrin as the chiral mobile phase additive in
The ' H and '% NMR spectra of 15 modified representatives of Troger's base were recorded and the corresponding signals assigned. In 'H NMR, the appearance of the AABB'CC'(XX) system, after irradiation of H,(H,), is deceptively simple and should not be first-order analysed. The 13C chemical shifts an
The 'H and I3C NMR spectra of an asymmetric Troger's base were recorded and the corresponding signals assigned on the basis of long-range coupling constants and 'H-13C correlations. In 1H NMR, ambiguities in the assignment of e m and endo hydrogen atoms and in the long-range couplings between the me
The 1H NMR spectra of a series of acridine-derived Tro gerÏs base analogs substituted at various positions were registered. Also the 1H NMR characteristics of the Ðrst heterocyclic asymmetric Tro gerÏs base analog constituted of one acridine and one phenanthroline nucleus with the two corresponding