✦ LIBER ✦

Stepwise autoproteolysis of presenilin 1 is affected by familial Alzheimer's disease mutations

✍ Scribed by Christian Haass; Akio Fukumori; Harald Steiner

Book ID: 118466099
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 49 KB
Volume: 6
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2010.05.315

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Monogenic determinants of familial Alzhe

Monogenic determinants of familial Alzheimer's disease: presenilin-1 mutations

✍ D. M. Kovacs; R. E. Tanzi 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 759 KB

Inhibition of neurite outgrowth by famil

Inhibition of neurite outgrowth by familial Alzheimer's disease-linked presenilin-1 mutations

✍ Wieslaw K. Dowjat; Thomas Wisniewski; Spiros Efthimiopoulos; Henryk M. Wisniewsk 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 316 KB

Monogenic determinants of familial Alzhe

Monogenic determinants of familial Alzheimer's disease: presenilin-2 mutations

✍ P. Renbaum; E. Levy-Lahad 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 178 KB

Homodimerization of presenilin N-termina

Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer’s disease

✍ Sara Cervantes; Roser Gonzàlez-Duarte; Gemma Marfany 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 346 KB

Sequence analyses of presenilin mutation

Sequence analyses of presenilin mutations linked to familial Alzheimer’s disease

✍ Sun Don Kim; Jinoh Kim 📂 Article 📅 2008 🏛 Springer Netherlands 🌐 English ⚖ 917 KB

Missense mutations in the chromosome 14

Missense mutations in the chromosome 14 familial Alzheimer's disease presenilin 1 gene

✍ Parvoneh Poorkaj; Vikram Sharma; Leojean Anderson; Ellen Nemens; Ma Elias Alonso 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB 👁 2 views

Mutations in the presenilin genes (PS-1 and PS-2) cause early onset autosomal dominant Alzheimer's disease (AD). Eight early-onset, autopsy-documented familial AD kindreds were screened for mutations in PS-1, and seven different mutations were identified. Three of these were new mutations (G209V, A4