Stem Cells and CNS Development

✍ Scribed by Sally Temple (auth.), Mahendra S. Rao (eds.)

Publisher: Humana Press
Year: 2001
Tongue: English
Leaves: 372
Series: Contemporary Neuroscience
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Stem cells were recently cited by Science magazine as the scientific breakthrough of the year because of their potential to revolutionize our understanding of the complexities of biological development. In Stem Cells and CNS Development, world renowned authorities in neural stem biology critically review the rapidly emerging findings on this critical class of stem cells, their involvement in neurogenesis and gliogenesis, and the therapeutic implications of these findings. The authors define by consensus the classes of stem cells in the nervous system, compare their similarities and differences, discuss the gains made in identifying human homologs of neural stem cells, and describe how these cells are beginning to be used for therapeutic purposes. Their examination includes all the major issues in stem cell biology, save apoptosis and cell cycle regulators.
Comprehensive and cutting-edge, Stem Cells and CNS Development provides all developmental scientists and neurobiologists not only an authoritative account of the current results in neural stem cell research, but also an incisive review of the rapidly emerging therapeutic uses of stem cells.

✦ Table of Contents

Front Matter....Pages i-x
Defining Neural Stem Cells and Their Role in Normal Development of the Nervous System....Pages 1-29
Multipotent Stem Cells in the Embryonic Nervous System....Pages 31-48
Multipotent Stem Cells in the Adult Central Nervous System....Pages 49-70
Glial Characteristics of Adult Subventricular Zone Stem Cells....Pages 71-92
Neuronal Restricted Precursors....Pages 93-121
Glial Restricted Precursors....Pages 123-151
PNS Precursor Cells....Pages 153-176
Neural Progenitor Cells of the Adult Human Brain....Pages 177-206
ES Cells and Neurogenesis....Pages 207-261
Mobilizing Endogenous Stem Cells....Pages 263-289
Transplant Therapy....Pages 291-305
Drug Discovery and Gene Discovery....Pages 307-325
Back Matter....Pages 327-370

✦ Subjects

Neurosciences

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