Neural Development and Stem Cells

✍ Scribed by Sally Temple (auth.), Mahendra S. Rao, Melissa Carpenter, Mohan C. Vemuri (eds.)

• Publisher: Springer-Verlag New York
• Year: 2012
• Tongue: English
• Leaves: 370
• Series: Stem Cell Biology and Regenerative Medicine
• Edition: 3
• Category: Library

✦ Synopsis

This expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system and the use of neural stem cells in clinical applications. Integrating new information about the use of development of neural stem cells for clinical applications, Drs. Rao, Carpenter and Vemuri have added additional chapters on neural transplantation and development of neural stem cells using reprogramming technologies. A new chapter on cancer in nervous system delineates how the fundamental biology of neural stem cells informs our understanding of cancer and tumor formation in the nervous system. Special attention is paid to the derivation of neural cells from embryonic stem cells and induced pluripotent stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, 3rd Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.

✦ Table of Contents

Front Matter....Pages i-xiii
Defining Neural Stem Cells and their Role in Normal Development of the Nervous System....Pages 1-30
Embryonic Stem Cells and Neurogenesis....Pages 31-59
The Cellular and Molecular Properties of Multipotent Neural Stem Cells....Pages 61-80
Multipotent Stem Cells in the Embryonic Nervous System....Pages 81-122
Neural Crest Formation and Diversification....Pages 123-147
Glial Nature of Adult Neural Stem Cells: Neurogenic Competence in Adult Astrocytes....Pages 149-172
Neural Stem Cell Death Regulation in Nervous System Development and Disease....Pages 173-200
Stem Cells of the Adult Olfactory Epithelium....Pages 201-222
Retinal Stem Cells....Pages 223-244
Transdifferentiation in the Nervous System....Pages 245-264
Neural and Dopaminergic Differentiation of Human Pluripotent Stem Cells....Pages 265-287
Mobilization of Neural Stem Cells in the Adult Central Nervous System....Pages 289-328
Stem Cell Pathways in Brain Tumors....Pages 329-349
Back Matter....Pages 351-363

✦ Subjects

Neurosciences