Isolation, Characterization and Utilization of CNS Stem Cells

✍ Scribed by I. L. Weissman (auth.), F. H. Gage Ph. D., Y. Christen Ph. D. (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1997
• Tongue: English
• Leaves: 202
• Series: Research and Perspectives in Neurosciences
• Edition: 1
• Category: Library

✦ Synopsis

Understanding the developmental origin of the nervous system is important for two reasons. This knowledge, first, is intellectually interesting since it provides an example of the assembly of a multicellular system, and second, will enable us to control the assembly and disassembly of this system in health and disease. This volume summarizes the current knowledge regarding the CNS stem cells which give rise to the nervous system.

✦ Table of Contents

Front Matter....Pages i-vii
Stem Cells: The Lessons from Hematopoieses....Pages 1-8
NRSF: A Coordinate Repressor of Neuron-Specific Genes Expressed in CNS Neural Progenitor Cells....Pages 9-27
Segregation of Cell Lineages in the Avian Neural Crest....Pages 29-42
Comparative Strategies of Subependymal Neurogenesis in the Adult Forebrain....Pages 43-65
Characterization of Neuronal Progenitor Cells of the Neonatal Forebrain....Pages 67-86
Neurogenesis in the Adult Brain: Prospects for Brain Repair....Pages 87-100
The Oligodendrocyte-Type-2 Astrocyte Lineage: In vitro and in vivo Studies on Development, Tissue Repair and Neoplasia....Pages 101-128
Neurogenesis in the Adult Brain: Lessons Learned from the Studies of Progenitor Cells from the Embryonic and Adult Central Nervous Systems....Pages 129-149
Use of Conditionally Immortalized Neural Progenitors for Transplantation and Gene Transfer to the CNS....Pages 151-168
The Origins of the Central Nervous System....Pages 169-172
Transplantation and Differentiation of Neural “Stem-Like” Cells: Possible Insights Into Development and Therapeutic Potential....Pages 173-196
Back Matter....Pages 197-199

✦ Subjects

Neurosciences