Statistics Applied to Clinical Trials

✍ Scribed by Ton J. Cleophas MD, PhD, Aeilko H. Zwinderman Math D, PhD, Toine F. Cleophas D Techn (auth.)

Publisher: Springer Netherlands
Year: 2002
Tongue: English
Leaves: 215
Category: Library

No coin nor oath required. For personal study only.

✦ Table of Contents

Front Matter....Pages i-xiii
Hypotheses, Data, Stratification....Pages 1-16
The Analysis of Efficacy Data of Drug Trials....Pages 17-38
The Analysis of Safety Data of Drug Trials....Pages 39-46
Equivalence Testing....Pages 47-52
Statistical Power and Sample Size....Pages 53-64
Interim Analyses....Pages 65-71
Multiple Statistical Inferences....Pages 73-82
Principles of Linear Regression....Pages 83-94
Subgroup Analysis using Multiple Linear Regression: Confounding, Interaction, Synergism....Pages 95-104
Curvilinear Regression....Pages 105-117
Meta-Analysis....Pages 119-132
Crossover Studies with Continuous Variables: Power Analysis....Pages 133-142
Crossover Studies with Binary Responses....Pages 143-150
Post-Hoc Analysis in Clinical Trials, a Case for Logistic Regression Analysis....Pages 151-155
Quality-of-Life Assessments in Clinical Trials....Pages 157-166
Statistical Analysis of Genetic Data....Pages 167-176
Relationship among Statistical Distributions....Pages 177-189
Statistics is Not “Bloodless” Algebra....Pages 191-197
Back Matter....Pages 199-210

✦ Subjects

Statistics for Life Sciences, Medicine, Health Sciences

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