In 1948, the first randomized controlled trial was published by the English Medical Research Council in the "British Medical Journal". Until then, observations had been uncontrolled. Initially, trials frequently did not confirm hypotheses to be tested. This phenomenon was attributed to little sensit
Statistics Applied to Clinical Trials
โ Scribed by T.J. Cleophas, Ton J. Cleophas, A.H. Zwinderman, Aeilko H. Zwinderman, T.F. Cleophas, Toine F. Cleophas, Eugene P. Cleophas
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Leaves
- 363
- Edition
- 3rd
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
Approaching the topic from an explanatory rather than mathematical stance, Cleophas and Zwinderman (both affiliated with the European Interuniversity College of Pharmaceutical Medicine Lyon, France) present a textbook designed for use in pharmaceutical education. They cover the use of statistical analyses in clinical trials, emphasizing such non-classical methods as equivalence testing, sequential analysis, multiple linear regression analyses for confounding, interaction, and synergism.
๐ SIMILAR VOLUMES
<P>The previous three editions of this book, rather than having been comprehensive, concentrated on the most relevant aspects of statistical analysis. Although well-received by students, clinicians, and researchers, these editions did not answer all of their questions. This updated and extended edit
<P>The previous three editions of this book, rather than having been comprehensive, concentrated on the most relevant aspects of statistical analysis. Although well-received by students, clinicians, and researchers, these editions did not answer all of their questions. This updated and extended edit
<p><P>From the reviews of the fourth edition:</P><P>"Readership: Students, physicians and investigators interested in statistical methods for clinical trials. This book was originally written for a course in medical statistics given in the EU sponsored program European Interuniversity Diploma of Pha