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Statistical uncertainty in the no-observed-adverse-effect level*1

✍ Scribed by BROWN, K


Book ID
121936440
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
860 KB
Volume
13
Category
Article
ISSN
0272-0590

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Statistical issues on the determination
✍ Takashi Yanagawa; Yasuki Kikuchi πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 182 KB

## Abstract The determination of a safe exposure level for toxic agents, often defined as the highest dose level with no toxic effect and termed the no‐observed‐adverse‐effect level (NOAEL) is reviewed. The conventional methods based on statistical tests are criticized, particularly when the sample