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Determination of an Acute No-Observed-Adverse-Effect Level (NOAEL) for Copper in Water

✍ Scribed by Magdalena Araya; Marie Clare McGoldrick; Leslie M. Klevay; J.J. Strain; Paula Robson; Forrest Nielsen; Manuel Olivares; Fernando Pizarro; LuAnn Johnson; Kenneth A. Poirier

Book ID: 115647074
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 95 KB
Volume: 34
Category: Article
ISSN: 0273-2300
DOI: 10.1006/rtph.2001.1492

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## Abstract The determination of a safe exposure level for toxic agents, often defined as the highest dose level with no toxic effect and termed the no‐observed‐adverse‐effect level (NOAEL) is reviewed. The conventional methods based on statistical tests are criticized, particularly when the sample