𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Statistical analysis strategies for association studies involving rare variants

✍ Scribed by Bansal, Vikas; Libiger, Ondrej; Torkamani, Ali; Schork, Nicholas J.

Book ID
109953277
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
464 KB
Volume
11
Category
Article
ISSN
1471-0056

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Bayesian analysis of rare variants in ge
Bayesian analysis of rare variants in genetic association studies
✍ Nengjun Yi; Degui Zhi πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 192 KB πŸ‘ 1 views

Recent advances in next-generation sequencing technologies facilitate the detection of rare variants, making it possible to uncover the roles of rare variants in complex diseases. As any single rare variants contain little variation, association analysis of rare variants requires statistical methods

Comparison of statistical tests for dise
Comparison of statistical tests for disease association with rare variants
✍ Saonli Basu; Wei Pan πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 173 KB πŸ‘ 1 views

In anticipation of the availability of next-generation sequencing data, there is increasing interest in investigating association between complex traits and rare variants (RVs). In contrast to association studies for common variants (CVs), due to the low frequencies of RVs, common wisdom suggests th

An evaluation of statistical approaches
An evaluation of statistical approaches to rare variant analysis in genetic association studies
✍ Andrew P. Morris; Eleftheria Zeggini πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 110 KB πŸ‘ 1 views

## Abstract Genome‐wide association (GWA) studies have proved to be extremely successful in identifying novel common polymorphisms contributing effects to the genetic component underlying complex traits. Nevertheless, one source of, as yet, undiscovered genetic determinants of complex traits are th