Stabilization of S-adenosyl-l-methionine promoted by trehalose
✍ Scribed by Alessandra Morana; Paola Stiuso; Giovanni Colonna; Monica Lamberti; Maria Cartenı̀; Mario De Rosa
- Book ID
- 117481027
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 94 KB
- Volume
- 1573
- Category
- Article
- ISSN
- 0304-4165
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📜 SIMILAR VOLUMES
## Abstract Two different strategies for the synthesis of S‐Adenosyl‐L‐methionine liphophilic derivatives have been attempted. The first chemical direct modification performed on S‐adenosyl‐L‐methionine is described.
Cation-exchange chromatography with sulfopropyl Sephadex was used to measure the levels of S-[methyl-3H]adenosyl-L-methionine synthesized by L1210 cells in vitro. Separation of S-[methyl-3H]adenosyl-L-methionine from [methyl-3H]methionine and other metabolites was achieved by stepwise elution with v