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Stabilization and activation of recombinant human immunodeficiency virus-1 reverse transcriptase-P66

✍ Scribed by Gerald L. Rowley; Qi-Feng Ma; Ian C. Bathurst; Philip J. Barr; George L. Kenyon


Book ID
115763661
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
534 KB
Volume
167
Category
Article
ISSN
0006-291X

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Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes