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Eukaryotic expression of enzymatically active human immunodeficiency virus type 1 reverse transcriptase

✍ Scribed by Maria G Isaguliants; Katja Pokrovskaya; Vladimir I Kashuba; Dmitrii Pokholok; Jorma Hinkula; Britta Wahren; Sergey N Kochetkov


Book ID
117110617
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
286 KB
Volume
447
Category
Article
ISSN
0014-5793

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Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes