## Abstract The GSβNS0 system is an important mammalian expression system used largely within industry for the highβlevel expression of recombinant proteins for therapeutic use. It is essential that the productivity of this system remains stable throughout culture expansion for the successful longβ
β¦ LIBER β¦
Stability of Recombinant Protein Production in the GS-NS0 Expression System Is Unaffected by Cryopreservation
β Scribed by Louise M. Barnes; Catherine M. Bentley; Alan J. Dickson
- Book ID
- 109386605
- Publisher
- American Institute of Chemical Engineers
- Year
- 2003
- Tongue
- English
- Weight
- 126 KB
- Volume
- 19
- Category
- Article
- ISSN
- 8756-7938
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## Abstract In this work, it was discovered that the stability of mRNA in a cellβfree extract could be controlled by using engineered T7 terminator sequences. Specifically, it was found that mRNA stability gradually decreased as the length of the stem structure of the T7 terminator was reduced sequ