SRN1 and oxidative addition reactions of nitroimidazole anions
β Scribed by Adelaide T.O.M. Adebayo; W.Russell Bowman; W.G. Salt
- Book ID
- 104218500
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 324 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
SLmaary: The anions of 2-and 4(5)-nitroimidazoles react with aliphatic substituted nitro canpxnds and pnitrobenzyl chloride by a S 1 mechanism, or by oxidative addition to the anion of 2-nitropropane, to yield l-alkyl-2-(3 4-)-nitroimidazoles.
π SIMILAR VOLUMES
Bunnett and his coworkers1 have successfully carried out many nucleophilic substitution reactions on simple halobeneenes under stimulation eitner by ammoniated electrons or light (around 300-380 nm) . These reactions according to them proceed via SDNl mechanism2. very ret ently
The ~afion of N-acetylthiomorpholinΒ’ 2 was studied in photostimdated reactions with iodobenzene la and l-iodonaphthalene lb in DMSO, giving good yields of the substitution products 3a and 3b by the SR~I mechanism. The reaction of la with 2 is also induced with FeBr2. l-Iodoadamantane 4 did not react