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Spontaneous Mutation: Genetic Control of Mutation Rates in Bacteriophage T4

โœ Scribed by DRAKE, JOHN W.; ALLEN, ELIZABETH F.; FORSBERG, SUSAN A.; PREPARATA, ROSA-MARIA; GREENING, ELAINE O.


Book ID
109665592
Publisher
Nature Publishing Group
Year
1969
Tongue
English
Weight
620 KB
Volume
221
Category
Article
ISSN
0028-0836

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A hotspot for transition mutations in th
โœ Singer, Britta Swebilius ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 729 KB

We have previously demonstrated that the sequence 5'TGGCAA 3' located at codons 32-33 of the rIIB gene of bacteriophage T4 is a hotspot for transition mutations (Nelson et al. 1981). Here I report the properties of the same TGGCAA sequence introduced into the gene at codons 11-12. The sequence is hi