Ultraviolet mutagenesis in bacteriophage T4 proceeds via error-prone repair (EPR) and requires the functional integrity of the uvsWXY system which mediates genetic recombination, recombinational repair, and mutability by diverse DNA damaging agents. Current opinion holds that mutagens acting through
β¦ LIBER β¦
Mutational specificity of a bacteriophage T4 DNA polymerase mutant, mel88
β Scribed by Reha-Krantz, Linda J.
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 445 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0026-8925
No coin nor oath required. For personal study only.
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## Abstract Adriamycin, daunomycin and ethidium, intercalating drugs which bind to doubleβ as well as singleβstranded DNA, inhibit phage T4 antimutator mutant CB121 DNA polymerase more strongly than the T4 wildβtype and the mutator L98 polymerase. In contrast, all three enzymes are inhibited equall