Sphingosine 1-phosphate (S1P) induces expression of E-selectin and adhesion of monocytes via intracellular signalling pathways in vascular endothelial cells
✍ Scribed by Tobias Weis; Wolfgang Völker; Rita Holtwick; Manaf Al Chahaf; Annette Schmidt
- Book ID
- 113582850
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 509 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0171-9335
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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate smooth muscle cell proliferation, migration, and vascular maturation. S1P increases the expression of several proteins including COX‐2 in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mecha